Numerical determination of OPE coefficients in the 3D Ising model from off-critical correlators

We propose a general method for the numerical evaluation of OPE coefficients in three dimensional Conformal Field Theories based on the study of the conformal perturbation of two point functions in the vicinity of the critical point. We test our proposal in the three dimensional Ising Model, looking at the magnetic perturbation of the , $<\sigma (\mathbf {r})\epsilon(0)>$ and correlators from which we extract the values of $C^{\sigma}_{\sigma\epsilon}=1.07(3)$ and $C^{\epsilon}_{\epsilon\epsilon}=1.45(30)$. Our estimate for $C^{\sigma}_{\sigma\epsilon}$ agrees with those recently obtained using conformal bootstrap methods, while $C^{\epsilon}_{\epsilon\epsilon}$, as far as we know, is new and could be used to further constrain conformal bootstrap analyses of the 3d Ising universality class.Comment: 4 pages, typos corrected, a few references adde

Tuning of frictional properties in torsional contact by means of disk grading

The contact of two surfaces in relative rotating motion occurs in many practical applications, from mechanical devices to human joints, displaying an intriguing interplay of effects at the onset of sliding due to the axisymmetric stress distribution. Theoretical and numerical models have been developed for some typical configurations, but work remains to be done to understand how to modify the emergent friction properties in this configuration. In this paper, we extend the two-dimensional (2D) spring-block model to investigate friction between surfaces in torsional contact. We investigate how the model describes the behavior of an elastic surface slowly rotating over a rigid substrate, comparing results with analytical calculations based on energy conservation. We show that an appropriate grading of the tribological properties of the surface can be used to avoid a non-uniform transition to sliding due to the axisymmetric configuration

A SCORM Thin Client Architecture for e-learning Systems based on Web Services

In this paper we propose an architecture of e-learning systems characterized by the use of Web services and a suitable middleware component. These technical infrastructures allow us to extend the system with new services as well as to integrate and reuse heterogeneous software e-learning components. Moreover, they let us better support the "anytime and anywhere " learning paradigm. As a matter of fact, the proposal provides an implementation of the run-time environment suggested in the sharable content object reference model (SCORM) to trace learning processes, which is also suitable for mobile learning

Exploiting Visual Languages Generation and UML Meta Modeling to Construct Meta-CASE Workbenches

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Exploiting XPG for Visual Languages Definition, Analysis and Development

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Ocular Refraction at Birth and Its Development During the First Year of Life in a Large Cohort of Babies in a Single Center in Northern Italy

The purpose of this study was to investigate refraction at birth and during the first year of life in a large cohort of babies born in a single center in Northern Italy. We also aimed to analyze refractive errors in relation to the gestational age at birth. An observational ophthalmological assessment was performed within 24 h of birth on 12,427 newborns. Refraction was examined using streak retinoscopy after the administration of tropicamide (1%). Values in the range of between +0.50 ≤ D ≤ +4.00 were defined as physiological refraction at birth. Newborns with refraction values outside of the physiological range were followed up during the first year of life. Comparative analyses were conducted in a subgroup of babies with known gestational ages. The following distribution of refraction at birth was recorded: 88.03% of the babies had physiological refraction, 5.03% had moderate hyperopia, 2.14% had severe hyperopia, 3.4%, had emmetropia, 0.45%, had myopia, 0.94% had astigmatism, and 0.01% had anisometropia. By the end of the first year of life, we observed reductions in hyperopia and astigmatism, and stabilization of myopia. Preterm babies had a four-fold higher risk of congenital myopia and a three-fold higher risk of congenital emmetropia as compared to term babies. Refraction profiles obtained at birth changed during the first year of life, leading to a normalization of the refraction values. Gestational age at birth affected the incidence of refractive errors and amblyopia

Evidence of friction reduction in laterally graded materials

In many biological structures, optimized mechanical properties are obtained through complex structural organization involvingmultiple constituents, functional grading and hierarchical organization. In the case of biological surfaces, the possibility to modifythe frictional and adhesive behaviour can also be achieved by exploiting a grading of the material properties. In this paper, we in-vestigate this possibility by considering the frictional sliding of elastic surfaces in the presence of a spatial variation of the Young’smodulus and the local friction coefficients. Using finite-element simulations and a two-dimensional spring-block model, we investi-gate how graded material properties affect the macroscopic frictional behaviour, in particular, static friction values and the transi-tion from static to dynamic friction. The results suggest that the graded material properties can be exploited to reduce static frictionwith respect to the corresponding non-graded material and to tune it to desired values, opening possibilities for the design of bio-inspired surfaces with tailor-made tribological propertie

Human-Animal Interaction in Animal-Assisted Interventions (AAI)s: Zoonosis Risks, Benefits, and Future Directions—A One Health Approach

: Animal-assisted interventions (AAI)s represent the expression of integrated medicine, according to the One Health approach. Actually, animal-assisted therapies and animal-assisted activities are implemented in hospitals, rehabilitation centers, etc. The efficacy of AAIs is based on interspecific interactions and would be impacted by different factors, such as the characters of both the animal and the handler, a suitable selection of animal species, an appropriate animal educational protocol, the relationship between the handler and the animal, and mutual relationship among the animal, the patients, and members of the working team. AAIs produce many advantages for the patients but could expose them to zoonotic-pathogens transmission. Therefore, positive animal welfare, as preventative medicine to avoid incidents or transmission of zoonosis, is a relevant aspect with implications for human and animal health and wellbeing. This review aims to summarize the current published knowledge regarding the occurrence of pathogens in AAIs and to discuss their relevance in light of health and safety in AAIs participants. In addition, this review will contribute to defining the state of the art of AAIs through a careful benefits/challenges analysis and offers discussion points on the possible future developments according to the One Health approach

Assessing the Usability of a Visual Tool for the definition of E-learning Processes

In this paper, we present a usability study aiming at assessing a visual language-based tool for developing adaptive e-learning processes. The tool implements the adaptive self-consistent learning object SET (ASCLO-S) visual language, a special case of flow diagrams, to be used by instructional designers to define classes of learners through stereotypes and to specify the more suited adaptive learning process for each class of learners. The usability study is based on the combined use of two techniques: a questionnaire-based survey and an empirical analysis. The survey has been used to achieve feedbacks from the subjects' point of view. In particular, it has been useful to capture the perceived usability of the subjects. The outcomes show that both the proposed visual notation and the system prototype are suitable for instructional designers with or without experience on the computer usage and on tools for defining e-learning processes. This result is further confirmed by the empirical analysis we carried out by analysing the correlation between the effort to develop adaptive e-learning processes and some measures suitable defined for those processes. Indeed, the empirical analysis revealed that the effort required to model e-learning processes is not influenced by the experience of the instructional designer with the use of e-learning tools, but it only depends on the size of the developed process

Effects of orexins on 17β-estradiol synthesis and P450 aromatase modulation in the testis of alpaca (Vicugna pacos).

The steroidogenic enzyme P450 aromatase (ARO) has a key role in the conversion of testosterone (T) into estrogens (E), expressed as 17β-estradiol. The presence and localization of this key enzyme have not been described before in the South American camelid alpaca (Vicugna pacos). In our previous studies of the expression and biological effects of orexin A (OxA) and OxB on the alpaca testis demonstrated that OxA, via its specific receptor 1 (OX1R), stimulated T synthesis. In order to extend these findings, we presently explored the presence and localization of ARO in the alpaca male gonad, and the possible correlation between ARO and the orexinergic complex. Western blotting and immunohistochemistry demonstrated the presence of ARO in tissue homogenates and its localization in the tubular and interstitial compartments of the alpaca testis, respectively. The addition of OxA to fresh testicular slices decreased the 17β-estradiol E levels. This effect was annulled by the sequential addition of the selective OX1R antagonist, SB-408124. OxB incubation did not have any effect on the biosynthesis of E. Furthermore, the OxA-mediated down-regulation of E secretion could be ascribed to ARO inhibition by exogenous OxA, as indicated by measurement of ARO activity in tissue slices incubated with OxA. Overall, our findings suggest that locally secreted OxA interacting with OX1R could indirectly inhibit ARO activity, disabling the conversion of T to E, and consequently lowering E biosynthesis and increasing the production of T in mammalian testis